VRT is supported by 15 years of research with clinical studies and papers published in more than 20 leading journals, of which some of the key findings can be summarized as:

  • Approximately 70% of patients experience positive outcome reflected by an increase in their visual field and studies have indicated an average increase of 4.9 degrees (Mueller I, et al., 2007; Romano JG, et al., 2008).
  • Elapsed time since injury does not seem to impact VRT therapies success. Therefore, a large historical backlog of patients can potentially be treated (Romano JG, et al., 2008).
  • Improvements are permanent and do not appear to be age or gender dependent.

The average approximate five-degree improvement in central vision from VRT can make a significant difference in patients’ daily lives ((Gall C, et al,. 2008) and patients experienced a functional improvement such as improvements in their vision that impact their ability to read, walk, watch TV, and socialize comfortably.

  1. Vision restoration through extrastriate stimulation in patients with visual field defects – a double-blind and randomized experimental study
    Autoren: Jobke S., Kasten E., Sabel B.A.
    Veröffentlichung: Neurorehabilitation and Neural Repair 2009; 23:246-255
  2. Visual field changes after a rehabilitation intervention: Vision Restoration Therapy
    Autoren: Romano J.G., Schulz P., Kenkel S., Todd D.P.
    Veröffentlichung: Journal of the Neurological Sciences 2008; 273:70-74
  3. Multifactorial predictors and outcome variables of vision restoration training in patients with post-geniculate visual field loss
    Autoren: Poggel D.A., Mueller I., Kasten E., Sabel B.A.
    Veröffentlichung: Restorative Neurology and Neuroscience 2008; 26:321-339
  4. Vision and health-related quality of life before and after vision restoration training in cerebrally damaged patients
    Autoren: Gall C., Mueller I., Gudlin J., Lindig A., Schlueter D., Jobke S., Franke G., Sabel B.A.
    Veröffentlichung: Restorative Neurology and Neuroscience 2008; 26:341-353
  5. The topography of training-induced visual field recovery: Perimetric maps and subjective representations
    Autoren: Poggel D.A., Mueller-Oehring E., Kasten E., Bunzenthal U., Sabel B.A.
    Veröffentlichung: Visual Cognition 2008; 16:1059
  6. Brain Activity Associated With Stimulation Therapy Of The Visual Border Zone In Hemianopic Stroke Patients
    Autoren: Marshall R.S., Ferrera J.J., Barnes A., Zang X., O’Brien K.A., Chmayssani M., Hirsch J., Lazar, R.M.
    Veröffentlichung: Neurorehabilitation and Neural Repair. 2008; 22:136-144
  7. Retinal Microperimetry as a Means to Assess Visual Field Expansion in Visual Restoration Therapy
    Autoren: Chmayssani M., Minzer B., Saxena N., Arogyasami R., Lazar R., Greenstein V.C., Marshall R.S.
    Veröffentlichung: Poster presented at the annual meeting of the American Academy of Neurology 2008
    Link http://www.researchgate.net/publication/238770947_Retinal_Microperimetry_as_a_Means_to_Assess_Visual_Field_Expansion_in_Visual_Restoration_Therapy
  8. Stability of the Blind Spot as a Measure of Fixation Stability in Visual Restoration Therapy
    Autoren: Marshall R.S., Schulz P., Kenkel S., Romano J.
    Veröffentlichung: Poster presented at the annual meeting of the American Academy of Neurology 2008
  9. Visual function in anterior ischemic optic neuropathy: Effect of Vision Restoration Therapy – A pilot study
    Autoren: Jung C.S., Bruce B., Newman N.J., Biousse V.
    Veröffentlichung: Journal of the Neurological Sciences 2008; 268:145-149
  10. Computer based Vision Restoration Therapy in glaucoma patients: A small open pilot study
    Autoren: Gudlin J., Mueller I., Thanos S., Sabel B.A.
    Veröffentlichung: Restorative Neurology and Neuroscience 2008; 26:403-412
  11. Recovery of visual field defects: A large clinical observational study using Visuelle RestitutionsTherapie
    Autoren: Mueller I., Mast H., Sabel B.A.
    Veröffentlichung: Restorative Neurology and Neuroscience. 2007; 25:563-572
  12. Effect of visual restitution training on absolute homonymous scotomas
    Autoren: Schreiber A., Vonthein R., Reinhard J., Trauzettel- Klosinski S., Connert C., Schiefer U.
    Veröffentlichung: Neurology 2006; 67:143-145
  13. Effects of long-term use of Vision Restoration Therapy (VRT) and stability of visual field improvements > 3 years
    Autoren: Gall C., Müller I., Kaufmann C., Sabel B.A.
    Veröffentlichung: Poster präsentiert beim jährlichen Meeting der North American Neuro-Ophthalmology Society 2006
  14. Visual field recovery after Vision Restoration Therapy (VRT) is independent of eye movements: An eye tracker study
    Autoren: Kasten E., Bunzenthal U., Sabel B.A.
    Veröffentlichung: Behavioural Brain Research 2006; 175:18-26
  15. Functional brain imaging, clinical and neurophysiological outcome of visual rehabilitation in a chronic stroke patient
    Autoren: Julkunen L., Tenovuo O., Vorobyev V., Hiltunen J., Teräs M., Jääskeläinen S., Hämäläinen H.
    Veröffentlichung: Restorative Neurology and Neuroscience 2006; 24:123-132
  16. Does VRT Change Absolute Homonymous Visual Field Defects? A Fundus-Controlled Study
    Autoren: Reinhard J., Schreiber A., Schiefer U., Kasten E., Sabel B.A., Kenkel S., Vonthein R., Trauzettel-Klosinski S.
    Veröffentlichung: British Journal of Ophthalmology, 2005; 89:30-35
  17. Vision Restoration Therapy (VRT) efficacy as assessed by comparative perimetric analysis and subjective questionnaires
    Authors: Sabel B.A., Kenkel S., Kasten E.
    Publication: Restorative Neurology and Neuroscience 2004; 22:399-420
  18. Attentional cueing improves Visuelle RestitutionsTherapie in patients with visual field defects
    Autoren: Poggel D.A., Kasten E., Sabel B.A.
    Veröffentlichung: Neurology, 2004; 63:2069-2076
  19. Vision Restoration Therapy after brain damage: subjective improvements of activities of daily life and their relationship to visual field enlargements
    Autoren: Mueller I., Poggel D.A., Kenkel S., Kasten E., Sabel B.A.
    Veröffentlichung: Visual Impairment Research 2003; 5: 157-178
  20. Stability of Visual Field Enlargements Following Computer-Based Restitution Training – Results of a Follow-up
    Autoren: Kasten E., Müller-Oehring E., Sabel B.A.
    Veröffentlichung: Journal of Clinical and Experimental Neuropsychology. 2001; 23:297-305
  21. Computer-based training for the treatment of partial blindness
    Autoren: Kasten E., Wuest S., Behrens-Baumann W., Sabel B.A.
    Veröffentlichung: Nature Medicine 1998; 4: 1083-1087
  22. Visual field enlargement after computer training in brain-damaged patients with homonymous deficits: an open pilot trial
    Authors: Kasten E., Sabel B.A.
    Publication: Restorative Neurology and Neuroscience. 1995; 8:113-127
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